Search results for " cooperativity"

showing 7 items of 7 documents

Dielectric spectroscopy of novel thiol-ene/epoxy thermosets obtained from allyl-modified hyperbranched poly (ethyleneimine) and diglycidylether of bi…

2019

[EN] Dielectric Thermal Analysis (DETA) of a series of new thermoset obtained by click chemistry was performed. The new thermosets were obtained by a dual-curing process consisting in a first photochemical thiol-ene, followed by a thermal thiol-epoxy starting from an allyl-terminated hyperbranched poly(ethyleneimine) (HBPEI) and different proportions of diglycidylether of bisphenol A (DGEBA) and the corresponding stoichiometric proportions of pentaerythritol tetrakis (3-mercaptopropionate, PETMP). The dielectric behaviour was obtained experimentally supressing the conductive effects. Two sub-Tg intramolecular non-cooperative gamma and beta relaxations and an intermolecular cooperative alpha…

Bisphenol AThermosetMaterials sciencePolymers and PlasticsSegmental cooperativityGeneral Physics and AstronomyThermosetting polymer02 engineering and technologyDielectric010402 general chemistry01 natural sciencesPentaerythritolDielectric thermal analysischemistry.chemical_compoundHyperbranched polymersCIENCIA DE LOS MATERIALES E INGENIERIA METALURGICAPolymer chemistryMaterials ChemistryEpoxy resinDielectric analysisOrganic ChemistryTermoplàsticsINGENIERIA DE LOS PROCESOS DE FABRICACIONEpoxyCiència dels materials021001 nanoscience & nanotechnology0104 chemical sciencesDielectric spectroscopychemistryIntramolecular forcevisual_artMAQUINAS Y MOTORES TERMICOSvisual_art.visual_art_medium0210 nano-technology
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Effect of sisal and hydrothermal ageing on the dielectric behaviour of polylactide/sisal biocomposites

2017

[EN] The dielectric properties of virgin polylactide (PLA) and its reinforced composites with different weight amounts of sisal fibres were assessed at broad temperature (from - 130 degrees C to 130 degrees C) and frequency ranges (from 10(-2)-10(7) Hz), before and after being subjected to accelerated hydrothermal ageing. The synergetic effects of both the loading of sisal and hydrothermal ageing were analysed by means of dielectric relaxation spectra. The relaxation time functions were evaluated by the Havriliak-Negami model, substracting the ohmic contribution of conductivity. The intramolecular and intermolecular relaxations were respectively analysed by means of Arrhenius and Vogel-Fulc…

Dielectric spectroscopyMaterials scienceSegmental cooperativity02 engineering and technologyDielectric010402 general chemistry01 natural sciencesHydrothermal circulationSisalCrystallinityDegradationDynamic fragilityPoly(lactide) (PLA)Composite materialCrystallinitySISALcomputer.programming_languageBiocompositesMaterials compostosTermoplàsticsGeneral EngineeringHydrothermal ageingINGENIERIA DE LOS PROCESOS DE FABRICACION021001 nanoscience & nanotechnology0104 chemical sciencesDielectric spectroscopyNatural fibreAgeingMAQUINAS Y MOTORES TERMICOSCeramics and CompositesDegradation (geology)0210 nano-technologycomputer
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The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin

2012

International audience; The acknowledged success of the Monod-Wyman-Changeux (MWC) allosteric model stems from its efficacy in accounting for the functional behavior of many complex proteins starting with hemoglobin (the paradigmatic case) and extending to channels and receptors. The kinetic aspects of the allosteric model, however, have been often neglected, with the exception of hemoglobin and a few other proteins where conformational relaxations can be triggered by a short and intense laser pulse, and monitored by time-resolved optical spectroscopy. Only recently the application of time-resolved wide-angle X-ray scattering (TR-WAXS), a direct structurally sensitive technique, unveiled th…

Models MolecularProtein ConformationcooperativityMESH: Catalytic DomainCooperativity01 natural sciencesMESH: Recombinant ProteinsHemoglobinsProtein structureMESH: Protein ConformationCatalytic Domainprotein structural dynamicsMESH: Allosteric Site0303 health sciencesMultidisciplinaryallosterybiologyMESH: KineticsChemistryBiological SciencesRecombinant Proteins[SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry Molecular Biology/BiophysicsMESH: HemoglobinsAllosteric SiteMESH: Models MolecularAdultMESH: MutationStereochemistryKineticsAllosteric regulation010402 general chemistry03 medical and health sciencesprotein conformational changesflash photolysisallostery; cooperativity; flash photolysis; hemoglobin; protein conformational changes; protein structural dynamics; time-resolved wide angle x ray scattering; time-resolved x-ray scatteringHumans030304 developmental biologytime-resolved X-ray scattering; protein conformational changes; cooperativity; flash photolysisMESH: Humanstime-resolved X-ray scatteringWild typeActive sitetime-resolved wide angle x ray scatteringMESH: AdulthemoglobinSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)0104 chemical sciencesprotein conformational changeKineticsAllosteric enzymeMutationbiology.proteinHemoglobin
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Effect of graphene nanoplatelets on the dielectric permittivity and segmental motions of electrospun poly(ethylene-co-vinyl alcohol) nanofibers

2021

The influence of the addition of graphene nanoplatelets (GNPs) on the intra/inter – molecular segmental motions of poly(ethylene-co-vinyl alcohol) (EVOH) was assessed by means of dielectric thermal analysis (DETA). The relaxation spectra were studied in terms of the dielectric permittivity (ε′) and the dielectric loss tangent (tan δ) at wide ranges of frequency (from 10−2 to 107 Hz) and temperature (from -150 to 140 °C). Two relaxation zones were disthinguished. Below the glass transition temperature (Tg), two β-relaxations were observed, which are characteristic local modes of mobility of the EVOH side groups, and related to the influence of the different surroundings of ethylene or vinyl …

Vinyl alcoholEngineeringTECNOLOGIA DE ALIMENTOSPolymers and PlasticsSegmental cooperativityDielectric permittivityPoly(ethylene-co-vinyl alcohol) EVOH02 engineering and technology010402 general chemistry01 natural scienceschemistry.chemical_compoundExfoliated graphite nano-plateletsRegional developmentDielectric permittivityDynamic fragilityMaterials ChemistryPoly ethylenebusiness.industryBusiness administrationPolymer nanocompositesEconomic support021001 nanoscience & nanotechnologyCondensed Matter Physics0104 chemical scienceschemistryMechanics of MaterialsMAQUINAS Y MOTORES TERMICOSChristian ministry0210 nano-technologybusinessGraphene nanoplatelets GNPsPolymer Degradation and Stability
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Molecular Mobility in Oriented and Unoriented Membranes Based on Poly[2-(Aziridin-1-yl)ethanol]

2021

Unoriented and oriented membranes based on dendronized polymers and copolymers obtained by chemical modification of poly[2-(aziridin-1-yl) ethanol] (PAZE) with the dendron 3,4,5-tris[4-(n-dodecan-1-yloxy)benzyloxy]benzoate were considered. DSC, XRD, CP-MAS NMR and DETA, contribute to characterize the tendency to crystallize, the molecular mobility of the benzyloxy substituent, the dendritic liquid crystalline group and the clearing transition. The orientation of the mesogenic chain somewhat hindered this molecular motion, especially in the full substituted PAZE. The fragility, free volume and thermal expansion coefficients of these membranes near the glass transition are related to the orie…

chemistry.chemical_classificationMaterials sciencePolymers and PlasticsMesogenSupramolecular chemistrySubstituentIonic bondingGeneral ChemistryPolymerQuímicaArticledielectric relaxation spectralcsh:QD241-441chemistry.chemical_compoundCrystallographyMembranepoly[2-(aziridin-1-yl)ethanol] (PAZE)chemistrylcsh:Organic chemistryDendrimerdendronic liquid crystal membranessegmental dynamicsmacromolecular cooperativityGlass transitionMaterialsPolymers
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Organocatalysts Fold to Generate an Active Site Pocket for the Mannich Reaction

2017

Catalysts containing urea, thiourea and tertiary amine groups fold into a three-dimensional organized structure in solution both in the absence as well as in the presence of substrates or substrate analogues, as indicated by solution NMR and computational studies. These foldamer catalysts promote Mannich reactions with both aliphatic and aromatic imines and malonate esters. Hammett plot and secondary kinetic isotope effects provide evidence for the C-C bond forming event as the turnoverlimiting step of the Mannich reaction. Computational studies suggest two viable pathways for the C-C bond formation step, differing in the activation modes of the malonate and imine substrates. The results sh…

inorganic chemicalsorganocatalysis bifunctional cooperativity mechanism kinetics computationsTertiary aminecooperativityIminemechanism010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundHammett equationMannich reactionOrganic chemistryorganocatalysista116Mannich reactionbiology010405 organic chemistryChemistryFoldamerActive siteGeneral ChemistryCombinatorial chemistrycomputations0104 chemical sciencesbifunctionalMalonatekineticsOrganocatalysisbiology.protein
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Halogen-Bonded Co-Crystals of Aromatic N-oxides : Polydentate Acceptors for Halogen and Hydrogen Bonds

2017

The C-ethyl-2-methylresorcinarene (1) forms 1:1 in-cavity complexes with aromatic N,N′-dioxides, only if each of the aromatic rings has an N−O group. The structurally different C-shaped 2,2′-bipyridine N,N′-dioxide (2,2′-BiPyNO) and the linear rod-shaped 4,4′-bipyridine N,N′-dioxide (4,4′-BiPyNO) both form 1:1 in-cavity complexes with the host resorcinarene in C4v crown and C2v conformations, respectively. In the solid state, the host–guest interactions between the 1,3-bis(4-pyridyl)propane N,N′-dioxide (BiPyPNO) and the host 1 stabilize the unfavorable anti-gauche conformation. Contrary to the N,N′-dioxide guests, the mono-N-oxide guest, 4-phenylpyridine N-oxide (4PhPyNO), does not form an…

polydentateDenticityGeneral Chemical EngineeringcooperativityInorganic chemistryCooperativity010402 general chemistry01 natural sciencesInorganic Chemistrychemistry.chemical_compounddiiodoperfluoroalkanesPyridinelcsh:QD901-999General Materials ScienceC−H···O interactionsta116hydrogen bondN−O groupHalogen bondvetysidokset010405 organic chemistryChemistryHydrogen bondH···O interactionsperfluoroalkylCondensed Matter Physicshalogen bond; hydrogen bond; aromatic N-oxides; perfluoroalkyl; diiodoperfluoroalkanes; polydentate; N−O group; cooperativity; C−H···O interactionsAcceptor0104 chemical sciencesaromatic N-oxidesCrystallographyHalogenorgaaninen kemiahalogen bondlcsh:CrystallographySingle crystalC−röntgenkristallografia
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